Louisville Cardinals - NCAAB Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Nov 25, 2020 | vs Evansville | REG | W | 79-44 | W | -21 | U | 125.5 |
| Nov 27, 2020 | vs Seton Hall | REG | W | 71-70 | L | -5.5 | O | 135.5 |
| Nov 29, 2020 | vs Prairie View A&M | REG | W | 86-64 | L | -26.5 | O | 140 |
| Dec 1, 2020 | vs Western Kentucky | REG | W | 75-54 | W | -4 | U | 142 |
| Dec 19, 2020 | @ Wisconsin | REG | L | 85-48 | L | +8.5 | O | 127.5 |
| Dec 22, 2020 | @ Pittsburgh | REG | W | 64-54 | W | -6 | U | 136.5 |
| Dec 26, 2020 | vs Kentucky | REG | W | 62-59 | L | -3.5 | U | 130.5 |
| Jan 2, 2021 | @ Boston College | REG | W | 76-64 | W | -6.5 | U | 143 |
| Jan 6, 2021 | vs Virginia Tech | REG | W | 73-71 | L | -3.5 | O | 131.5 |
| Jan 13, 2021 | @ Wake Forest | REG | W | 77-65 | W | -7.5 | O | 136 |
| Jan 16, 2021 | @ Miami | REG | L | 78-72 | L | -4.5 | O | 132 |
| Jan 18, 2021 | vs Florida State | REG | L | 78-65 | L | -4 | O | 141.5 |
| Jan 23, 2021 | vs Duke | REG | W | 70-65 | W | -2.5 | U | 142 |
| Jan 27, 2021 | @ Clemson | REG | L | 54-50 | L | +1.5 | U | 130 |
| Feb 1, 2021 | vs Georgia Tech | REG | W | 74-58 | W | -5 | U | 135 |
| Feb 20, 2021 | @ North Carolina | REG | L | 99-54 | L | +4.5 | O | 141.5 |
| Feb 23, 2021 | vs Notre Dame | REG | W | 69-57 | W | -4 | U | 142 |
| Feb 27, 2021 | @ Duke | REG | W | 80-73 | W | +5 | O | 140.5 |
| Mar 6, 2021 | vs Virginia | REG | L | 68-58 | L | +1.5 | O | 122 |
| Mar 10, 2021 | vs Duke | REG | L | 70-56 | L | +3 | U | 140.5 |
