Saskatchewan Roughriders - CFL Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 6, 2021 | vs British Columbia | REG | W | 33-29 | L | -6.5 | O | 47 |
| Aug 14, 2021 | vs Hamilton | REG | W | 30-8 | W | -1.5 | U | 49.5 |
| Aug 21, 2021 | vs Ottawa | REG | W | 23-10 | W | -10 | U | 46.5 |
| Sep 5, 2021 | vs Winnipeg | REG | L | 23-8 | L | -5 | U | 43.5 |
| Sep 11, 2021 | @ Winnipeg | REG | L | 33-9 | L | +2.5 | U | 43 |
| Sep 17, 2021 | vs Toronto | REG | W | 30-16 | W | -4.5 | O | 44 |
| Sep 24, 2021 | @ British Columbia | REG | W | 31-24 | W | -1 | O | 47 |
| Oct 2, 2021 | @ Calgary | REG | L | 23-17 | L | -2.5 | U | 47.5 |
| Oct 9, 2021 | vs Calgary | REG | L | 22-19 | L | -6.5 | U | 45 |
| Oct 23, 2021 | @ Calgary | REG | W | 20-17 | W | +2 | U | 44.5 |
| Oct 30, 2021 | @ Montreal | REG | W | 19-14 | W | -1.5 | U | 46 |
| Nov 5, 2021 | @ Edmonton | REG | W | 19-17 | L | -7 | U | 46 |
| Nov 13, 2021 | vs Edmonton | REG | W | 29-24 | L | -11.5 | O | 43 |
| Nov 20, 2021 | @ Hamilton | REG | L | 24-3 | L | +5.5 | U | 41.5 |
| Nov 28, 2021 | vs Calgary | PST | W | 33-30 | W | -2.5 | O | 42 |
| Dec 5, 2021 | @ Winnipeg | PST | L | 21-17 | W | +8.5 | U | 43 |
