Purdue Boilermakers - NCAAF Schedule for 2022
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 1, 2022 | vs Penn State | REG | L | 35-31 | L | +3.5 | O | 53.5 |
| Sep 10, 2022 | vs Indiana State | REG | W | 56-0 | W | -37 | O | 54 |
| Sep 17, 2022 | @ Syracuse | REG | L | 32-29 | L | +1.5 | O | 59.5 |
| Sep 24, 2022 | vs Florida Atlantic | REG | W | 28-26 | L | -16 | U | 57 |
| Oct 1, 2022 | @ Minnesota | REG | W | 20-10 | W | +9 | U | 53 |
| Oct 8, 2022 | @ Maryland | REG | W | 31-29 | W | +3 | O | 59.5 |
| Oct 15, 2022 | vs Nebraska | REG | W | 43-37 | L | -14 | O | 56 |
| Oct 22, 2022 | @ Wisconsin | REG | L | 35-24 | L | +1.5 | O | 51.5 |
| Nov 5, 2022 | vs Iowa | REG | L | 24-3 | L | -3.5 | U | 39.5 |
| Nov 12, 2022 | @ Illinois | REG | W | 31-24 | W | +6 | O | 44 |
| Nov 19, 2022 | vs Northwestern | REG | W | 17-9 | L | -17.5 | U | 44.5 |
| Nov 26, 2022 | @ Indiana | REG | W | 30-16 | W | -10 | U | 53 |
| Dec 3, 2022 | @ Michigan | REG | L | 43-22 | L | +15 | O | 54 |
| Jan 2, 2023 | vs Louisiana State | PST | L | 63-7 | L | +15 | O | 54.5 |
