New England Patriots - NFL Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 12, 2021 | vs Washington | PRE | W | 22-13 | W | -2 | U | 37 |
| Aug 19, 2021 | @ Philadelphia | PRE | W | 35-0 | W | +1 | U | 38.5 |
| Aug 29, 2021 | @ NY Giants | PRE | W | 22-20 | L | -3.5 | O | 36 |
| Sep 12, 2021 | vs Miami | REG | L | 17-16 | L | -3.5 | U | 43 |
| Sep 19, 2021 | @ NY Jets | REG | W | 25-6 | W | -5.5 | U | 43 |
| Sep 26, 2021 | vs New Orleans | REG | L | 28-13 | L | -3 | U | 43.5 |
| Oct 3, 2021 | vs Tampa Bay | REG | L | 19-17 | W | +6.5 | U | 49 |
| Oct 10, 2021 | @ Houston | REG | W | 25-22 | L | -8 | O | 39 |
| Oct 17, 2021 | vs Dallas | REG | L | 35-29 | L | +3.5 | O | 50.5 |
| Oct 24, 2021 | vs NY Jets | REG | W | 54-13 | W | -7 | O | 42.5 |
| Oct 31, 2021 | @ LA Chargers | REG | W | 27-24 | W | +3.5 | O | 50.5 |
| Nov 7, 2021 | @ Carolina | REG | W | 24-6 | W | -3.5 | U | 41.5 |
| Nov 14, 2021 | vs Cleveland | REG | W | 45-7 | W | -2.5 | O | 44.5 |
| Nov 18, 2021 | @ Atlanta | REG | W | 25-0 | W | -7 | U | 47 |
| Nov 28, 2021 | vs Tennessee | REG | W | 36-13 | W | -7 | O | 43 |
| Dec 6, 2021 | @ Buffalo | REG | W | 14-10 | W | +3 | U | 40 |
| Dec 18, 2021 | @ Indianapolis | REG | L | 27-17 | L | +1 | U | 46.5 |
| Dec 26, 2021 | vs Buffalo | REG | L | 33-21 | L | -1 | O | 43.5 |
| Jan 2, 2022 | vs Jacksonville | REG | W | 50-10 | W | -17 | O | 41.5 |
| Jan 9, 2022 | @ Miami | REG | L | 33-24 | L | -6 | O | 41 |
| Jan 15, 2022 | @ Buffalo | PST | L | 47-17 | L | +4.5 | O | 43 |
