Buffalo Bills - NFL Schedule for 2022
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 13, 2022 | vs Indianapolis | PRE | W | 27-24 | W | +1 | O | 37.5 |
| Aug 20, 2022 | vs Denver | PRE | W | 42-15 | W | -7 | O | 42 |
| Aug 26, 2022 | @ Carolina | PRE | L | 21-0 | L | +5 | U | 41 |
| Sep 8, 2022 | @ LA Rams | REG | W | 31-10 | W | -2.5 | U | 52 |
| Sep 19, 2022 | vs Tennessee | REG | W | 41-7 | W | -10 | O | 47.5 |
| Sep 25, 2022 | @ Miami | REG | L | 21-19 | L | -4 | U | 54.5 |
| Oct 2, 2022 | @ Baltimore | REG | W | 23-20 | P | -3 | U | 50.5 |
| Oct 9, 2022 | vs Pittsburgh | REG | W | 38-3 | W | -14 | U | 44.5 |
| Oct 16, 2022 | @ Kansas City | REG | W | 24-20 | W | -2.5 | U | 54.5 |
| Oct 30, 2022 | vs Green Bay | REG | W | 27-17 | L | -10.5 | U | 47 |
| Nov 6, 2022 | @ NY Jets | REG | L | 20-17 | L | -10.5 | U | 46 |
| Nov 13, 2022 | vs Minnesota | REG | L | 33-30 | L | -6.5 | O | 46.5 |
| Nov 20, 2022 | vs Cleveland | REG | W | 31-23 | W | -7.5 | O | 50.5 |
| Nov 24, 2022 | @ Detroit | REG | W | 28-25 | L | -9.5 | U | 54.5 |
| Dec 1, 2022 | @ New England | REG | W | 24-10 | W | -4 | U | 44 |
| Dec 11, 2022 | vs NY Jets | REG | W | 20-12 | L | -10 | U | 43.5 |
| Dec 17, 2022 | vs Miami | REG | W | 32-29 | L | -7 | O | 44.5 |
| Dec 24, 2022 | @ Chicago | REG | W | 35-13 | W | -8 | O | 40.5 |
| Jan 8, 2023 | vs New England | REG | W | 35-23 | W | -8 | O | 44 |
| Jan 15, 2023 | vs Miami | PST | W | 34-31 | L | -14 | O | 44.5 |
| Jan 22, 2023 | vs Cincinnati | PST | L | 27-10 | L | -5.5 | U | 48.5 |
