Carolina Panthers - NFL Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 15, 2021 | @ Indianapolis | PRE | L | 21-18 | P | +3 | O | 33 |
| Aug 21, 2021 | vs Baltimore | PRE | L | 20-3 | L | +3.5 | U | 34.5 |
| Aug 27, 2021 | vs Pittsburgh | PRE | W | 34-9 | W | -4 | O | 35.5 |
| Sep 12, 2021 | vs NY Jets | REG | W | 19-14 | W | -3.5 | U | 44.5 |
| Sep 19, 2021 | vs New Orleans | REG | W | 26-7 | W | +3 | U | 45 |
| Sep 23, 2021 | @ Houston | REG | W | 24-9 | W | -8 | U | 43 |
| Oct 3, 2021 | @ Dallas | REG | L | 36-28 | L | +4.5 | O | 51.5 |
| Oct 10, 2021 | vs Philadelphia | REG | L | 21-18 | L | -2.5 | U | 46 |
| Oct 17, 2021 | vs Minnesota | REG | L | 34-28 | L | +2.5 | O | 45.5 |
| Oct 24, 2021 | @ NY Giants | REG | L | 25-3 | L | -3 | U | 43 |
| Oct 31, 2021 | @ Atlanta | REG | W | 19-13 | W | +2.5 | U | 46.5 |
| Nov 7, 2021 | vs New England | REG | L | 24-6 | L | +3.5 | U | 41.5 |
| Nov 14, 2021 | @ Arizona | REG | W | 34-10 | W | +7 | O | 41.5 |
| Nov 21, 2021 | vs Washington | REG | L | 27-21 | L | -3.5 | O | 43 |
| Nov 28, 2021 | @ Miami | REG | L | 33-10 | L | -1.5 | O | 40.5 |
| Dec 12, 2021 | vs Atlanta | REG | L | 29-21 | L | -2.5 | O | 41.5 |
| Dec 19, 2021 | @ Buffalo | REG | L | 31-14 | L | +14.5 | O | 43 |
| Dec 26, 2021 | vs Tampa Bay | REG | L | 32-6 | L | +11 | U | 44.5 |
| Jan 2, 2022 | @ New Orleans | REG | L | 18-10 | L | +7 | U | 37 |
| Jan 9, 2022 | @ Tampa Bay | REG | L | 41-17 | L | +10.5 | O | 43 |
