New York Giants - NFL Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 14, 2021 | vs NY Jets | PRE | L | 12-7 | L | +2.5 | U | 33.5 |
| Aug 22, 2021 | @ Cleveland | PRE | L | 17-13 | W | +6 | U | 35 |
| Aug 29, 2021 | vs New England | PRE | L | 22-20 | W | +3.5 | O | 36 |
| Sep 12, 2021 | vs Denver | REG | L | 27-13 | L | +3 | U | 41.5 |
| Sep 16, 2021 | @ Washington | REG | L | 30-29 | W | +4 | O | 41.5 |
| Sep 26, 2021 | vs Atlanta | REG | L | 17-14 | L | -2.5 | U | 47.5 |
| Oct 3, 2021 | @ New Orleans | REG | W | 27-21 | W | +7 | O | 42.5 |
| Oct 10, 2021 | @ Dallas | REG | L | 44-20 | L | +7 | O | 53 |
| Oct 17, 2021 | vs LA Rams | REG | L | 38-11 | L | +7.5 | P | 49 |
| Oct 24, 2021 | vs Carolina | REG | W | 25-3 | W | +3 | U | 43 |
| Nov 1, 2021 | @ Kansas City | REG | L | 20-17 | W | +10.5 | U | 53 |
| Nov 7, 2021 | vs Las Vegas | REG | W | 23-16 | W | +3 | U | 47 |
| Nov 22, 2021 | @ Tampa Bay | REG | L | 30-10 | L | +10.5 | U | 50 |
| Nov 28, 2021 | vs Philadelphia | REG | W | 13-7 | W | +4 | U | 45.5 |
| Dec 5, 2021 | @ Miami | REG | L | 20-9 | L | +7 | U | 40 |
| Dec 12, 2021 | @ LA Chargers | REG | L | 37-21 | L | +9 | O | 43.5 |
| Dec 19, 2021 | vs Dallas | REG | L | 21-6 | L | +12 | U | 43.5 |
| Dec 26, 2021 | @ Philadelphia | REG | L | 34-10 | L | +11 | O | 41 |
| Jan 2, 2022 | @ Chicago | REG | L | 29-3 | L | +6.5 | U | 36.5 |
| Jan 9, 2022 | vs Washington | REG | L | 22-7 | L | +6 | U | 36 |
