Cleveland Guardians - MLB Schedule for 2021
| Date | Opponent | Game | Result | Score | Line | OU | Total |
|---|---|---|---|---|---|---|---|
| Apr 1, 2021 | @ Detroit | REG | L | 3-2 | -175 | U | 7.5 |
| Apr 3, 2021 | @ Detroit | REG | L | 5-2 | -157 | U | 8 |
| Apr 4, 2021 | @ Detroit | REG | W | 9-3 | -130 | O | 8 |
| Apr 5, 2021 | vs Kansas City | REG | L | 3-0 | -132 | U | 9 |
| Apr 7, 2021 | vs Kansas City | REG | W | 4-2 | -182 | U | 8 |
| Apr 9, 2021 | vs Detroit | REG | W | 4-1 | -185 | U | 9.5 |
| Apr 10, 2021 | vs Detroit | REG | W | 11-3 | -160 | O | 9 |
| Apr 11, 2021 | vs Detroit | REG | W | 5-2 | -166 | U | 9.5 |
| Apr 12, 2021 | @ Chi White Sox | REG | L | 4-3 | +110 | U | 8 |
| Apr 13, 2021 | @ Chi White Sox | REG | W | 2-0 | +103 | U | 6.5 |
| Apr 14, 2021 | @ Chi White Sox | REG | L | 8-0 | +100 | O | 7.5 |
| Apr 15, 2021 | @ Chi White Sox | REG | W | 4-2 | +144 | U | 7.5 |
| Apr 16, 2021 | @ Cincinnati | REG | L | 10-3 | +110 | O | 9 |
| Apr 17, 2021 | @ Cincinnati | REG | L | 3-2 | +125 | U | 8 |
| Apr 18, 2021 | @ Cincinnati | REG | W | 6-3 | -158 | O | 7 |
| Apr 20, 2021 | vs Chi White Sox | REG | L | 8-5 | -105 | O | 7 |
| Apr 22, 2021 | vs NY Yankees | REG | L | 6-3 | -110 | O | 8 |
| Apr 23, 2021 | vs NY Yankees | REG | L | 5-3 | +145 | U | 8.5 |
| Apr 24, 2021 | vs NY Yankees | REG | L | 2-1 | +105 | U | 6.5 |
| Apr 25, 2021 | vs NY Yankees | REG | W | 7-3 | +113 | O | 8 |
| Apr 26, 2021 | vs Minnesota | REG | W | 5-3 | +112 | P | 8 |
| Apr 27, 2021 | vs Minnesota | REG | W | 7-4 | +106 | O | 8.5 |
| Apr 28, 2021 | vs Minnesota | REG | L | 10-2 | +108 | O | 9.5 |
| Apr 30, 2021 | @ Chi White Sox | REG | W | 5-3 | -142 | O | 6.5 |
| May 1, 2021 | @ Chi White Sox | REG | L | 7-3 | +160 | O | 8.5 |
| May 2, 2021 | @ Chi White Sox | REG | W | 5-0 | +144 | U | 8 |
| May 3, 2021 | @ Kansas City | REG | W | 8-6 | -112 | O | 8.5 |
| May 4, 2021 | @ Kansas City | REG | W | 7-3 | +131 | O | 9 |
| May 5, 2021 | @ Kansas City | REG | W | 5-4 | -156 | O | 7 |
| May 6, 2021 | @ Kansas City | REG | W | 4-0 | +120 | U | 8 |
| May 7, 2021 | vs Cincinnati | REG | L | 3-0 | -137 | U | 8 |
| May 8, 2021 | vs Cincinnati | REG | W | 9-2 | -118 | O | 8 |
| May 11, 2021 | vs Chi Cubs | REG | W | 3-2 | -180 | U | 7 |
| May 12, 2021 | vs Chi Cubs | REG | W | 2-1 | -132 | U | 8.5 |
| May 13, 2021 | @ Seattle | REG | W | 4-2 | -116 | U | 7.5 |
| May 14, 2021 | @ Seattle | REG | L | 7-3 | -110 | O | 7.5 |
| May 15, 2021 | @ Seattle | REG | L | 7-3 | -106 | O | 8.5 |
| May 16, 2021 | @ Seattle | REG | L | 3-2 | -190 | U | 7.5 |
| May 17, 2021 | @ LA Angels | REG | L | 7-4 | +123 | O | 9.5 |
| May 18, 2021 | @ LA Angels | REG | W | 6-5 | -105 | O | 7.5 |
| May 19, 2021 | @ LA Angels | REG | W | 3-2 | +107 | U | 8 |
| May 21, 2021 | vs Minnesota | REG | L | 10-0 | -125 | O | 9 |
| May 22, 2021 | vs Minnesota | REG | W | 5-3 | -163 | O | 7.5 |
| May 23, 2021 | vs Minnesota | REG | L | 8-5 | -138 | O | 9 |
| May 24, 2021 | @ Detroit | REG | W | 6-5 | +118 | O | 8.5 |
| May 25, 2021 | @ Detroit | REG | W | 4-1 | -142 | U | 9 |
| May 26, 2021 | @ Detroit | REG | L | 1-0 | -121 | U | 9.5 |
| May 27, 2021 | @ Detroit | REG | W | 5-2 | -159 | P | 7 |
| May 28, 2021 | vs Toronto | REG | L | 11-2 | +155 | O | 7.5 |
| May 30, 2021 | vs Toronto | REG | L | 4-1 | -105 | U | 6.5 |
| May 30, 2021 | vs Toronto | REG | W | 6-5 | +145 | O | 7 |
| May 31, 2021 | vs Chi White Sox | REG | L | 8-6 | +145 | O | 5.5 |
| May 31, 2021 | vs Chi White Sox | REG | W | 3-1 | +100 | U | 7 |
| Jun 1, 2021 | vs Chi White Sox | REG | W | 6-5 | -162 | O | 7 |
| Jun 4, 2021 | @ Baltimore | REG | L | 3-1 | -105 | U | 8.5 |
| Jun 5, 2021 | @ Baltimore | REG | W | 10-4 | +112 | O | 8.5 |
| Jun 6, 2021 | @ Baltimore | REG | L | 18-5 | -112 | O | 9 |
| Jun 8, 2021 | @ St. Louis | REG | W | 10-1 | -156 | O | 7 |
| Jun 9, 2021 | @ St. Louis | REG | L | 8-2 | +120 | O | 8 |
| Jun 11, 2021 | vs Seattle | REG | W | 7-0 | -150 | U | 9 |
| Jun 12, 2021 | vs Seattle | REG | W | 5-4 | -115 | O | 8 |
| Jun 13, 2021 | vs Seattle | REG | L | 6-2 | -220 | O | 7.5 |
| Jun 14, 2021 | vs Baltimore | REG | W | 4-3 | -158 | U | 8.5 |
| Jun 15, 2021 | vs Baltimore | REG | W | 7-2 | -166 | O | 8.5 |
| Jun 16, 2021 | vs Baltimore | REG | W | 8-7 | -153 | O | 8 |
| Jun 17, 2021 | vs Baltimore | REG | W | 10-3 | -114 | O | 9.5 |
| Jun 18, 2021 | @ Pittsburgh | REG | L | 11-10 | -129 | O | 9 |
| Jun 19, 2021 | @ Pittsburgh | REG | L | 6-3 | -115 | O | 8.5 |
| Jun 20, 2021 | @ Pittsburgh | REG | W | 2-1 | +119 | U | 8 |
| Jun 21, 2021 | @ Chi Cubs | REG | W | 4-0 | +129 | U | 7 |
| Jun 22, 2021 | @ Chi Cubs | REG | L | 7-1 | +170 | U | 8.5 |
| Jun 24, 2021 | @ Minnesota | REG | W | 4-1 | +169 | U | 9.5 |
| Jun 25, 2021 | @ Minnesota | REG | L | 8-7 | +115 | O | 9.5 |
| Jun 27, 2021 | @ Minnesota | REG | L | 8-2 | +120 | O | 9.5 |
| Jun 28, 2021 | vs Detroit | REG | W | 13-5 | -154 | O | 9.5 |
| Jun 30, 2021 | vs Detroit | REG | L | 9-4 | -175 | O | 7.5 |
| Jun 30, 2021 | vs Detroit | REG | L | 7-1 | -133 | P | 8 |
| Jul 1, 2021 | vs Houston | REG | L | 7-2 | +161 | O | 8.5 |
| Jul 2, 2021 | vs Houston | REG | L | 6-3 | +143 | O | 8.5 |
| Jul 3, 2021 | vs Houston | REG | L | 3-2 | +129 | U | 9.5 |
| Jul 4, 2021 | vs Houston | REG | L | 4-3 | +127 | U | 9 |
| Jul 5, 2021 | @ Tampa Bay | REG | L | 9-8 | +170 | O | 8.5 |
| Jul 7, 2021 | @ Tampa Bay | REG | L | 8-1 | +140 | O | 7 |
| Jul 7, 2021 | @ Tampa Bay | REG | L | 4-0 | +180 | U | 6.5 |
| Jul 8, 2021 | vs Kansas City | REG | W | 7-4 | -135 | O | 9 |
| Jul 9, 2021 | vs Kansas City | REG | W | 2-1 | -143 | U | 9.5 |
| Jul 10, 2021 | vs Kansas City | REG | W | 14-6 | -125 | O | 9 |
| Jul 16, 2021 | @ Oakland | REG | L | 5-4 | +170 | O | 8 |
| Jul 17, 2021 | @ Oakland | REG | W | 3-2 | +162 | U | 8.5 |
| Jul 18, 2021 | @ Oakland | REG | W | 4-2 | +149 | U | 8 |
| Jul 19, 2021 | @ Houston | REG | L | 4-3 | +190 | U | 9 |
| Jul 20, 2021 | @ Houston | REG | L | 9-3 | +185 | O | 8.5 |
| Jul 21, 2021 | @ Houston | REG | W | 5-4 | +220 | O | 8.5 |
| Jul 22, 2021 | vs Tampa Bay | REG | L | 5-4 | +119 | U | 9.5 |
| Jul 23, 2021 | vs Tampa Bay | REG | L | 10-5 | +114 | O | 9.5 |
| Jul 24, 2021 | vs Tampa Bay | REG | L | 8-2 | +141 | U | 10.5 |
| Jul 25, 2021 | vs Tampa Bay | REG | W | 3-2 | +155 | U | 9 |
| Jul 27, 2021 | vs St. Louis | REG | L | 4-2 | +107 | U | 9.5 |
| Jul 28, 2021 | vs St. Louis | REG | W | 7-2 | +100 | O | 8.5 |
| Jul 30, 2021 | @ Chi White Sox | REG | L | 6-4 | +205 | O | 8 |
| Jul 31, 2021 | @ Chi White Sox | REG | W | 12-11 | +141 | O | 9 |
| Aug 1, 2021 | @ Chi White Sox | REG | L | 2-1 | +155 | U | 9.5 |
| Aug 2, 2021 | @ Toronto | REG | W | 5-2 | +230 | U | 9 |
| Aug 3, 2021 | @ Toronto | REG | L | 7-2 | +185 | P | 9 |
| Aug 4, 2021 | @ Toronto | REG | L | 8-6 | +180 | O | 9.5 |
| Aug 5, 2021 | @ Toronto | REG | L | 3-0 | +183 | U | 9 |
| Aug 6, 2021 | vs Detroit | REG | W | 6-1 | -140 | U | 9.5 |
| Aug 7, 2021 | vs Detroit | REG | L | 2-1 | -150 | U | 9.5 |
| Aug 8, 2021 | vs Detroit | REG | W | 7-5 | -155 | O | 9.5 |
| Aug 9, 2021 | vs Cincinnati | REG | W | 9-3 | +160 | O | 9.5 |
| Aug 10, 2021 | vs Oakland | REG | L | 4-3 | +132 | U | 9.5 |
| Aug 11, 2021 | vs Oakland | REG | L | 6-3 | +140 | U | 9.5 |
| Aug 12, 2021 | vs Oakland | REG | L | 17-0 | +158 | O | 9.5 |
| Aug 13, 2021 | @ Detroit | REG | W | 7-4 | -118 | O | 9.5 |
| Aug 14, 2021 | @ Detroit | REG | L | 6-4 | +115 | O | 9.5 |
| Aug 15, 2021 | @ Detroit | REG | W | 11-0 | -140 | O | 9 |
| Aug 16, 2021 | @ Minnesota | REG | L | 5-4 | +113 | U | 9.5 |
| Aug 17, 2021 | @ Minnesota | REG | W | 3-1 | +150 | U | 9.5 |
| Aug 18, 2021 | @ Minnesota | REG | L | 8-7 | -102 | O | 9.5 |
| Aug 20, 2021 | vs LA Angels | REG | W | 9-1 | -120 | O | 9.5 |
| Aug 21, 2021 | vs LA Angels | REG | W | 5-1 | -127 | U | 9 |
| Aug 22, 2021 | vs LA Angels | REG | W | 3-0 | -115 | U | 9 |
| Aug 24, 2021 | vs Texas | REG | L | 7-3 | -170 | O | 9 |
| Aug 25, 2021 | vs Texas | REG | W | 7-2 | -200 | P | 9 |
| Aug 26, 2021 | vs Texas | REG | W | 10-6 | -153 | O | 9.5 |
| Aug 27, 2021 | vs Boston | REG | L | 4-3 | +150 | U | 9.5 |
| Aug 28, 2021 | vs Boston | REG | L | 5-3 | +122 | U | 9 |
| Aug 29, 2021 | vs Boston | REG | W | 7-5 | +141 | O | 10 |
| Aug 31, 2021 | @ Kansas City | REG | W | 7-2 | +105 | O | 8.5 |
| Sep 1, 2021 | @ Kansas City | REG | W | 5-3 | +115 | U | 9 |
| Sep 2, 2021 | @ Kansas City | REG | W | 4-2 | -103 | U | 8.5 |
| Sep 3, 2021 | @ Boston | REG | L | 8-5 | +150 | O | 9 |
| Sep 4, 2021 | @ Boston | REG | L | 4-3 | +170 | U | 9.5 |
| Sep 5, 2021 | @ Boston | REG | W | 11-5 | +123 | O | 9.5 |
| Sep 6, 2021 | vs Minnesota | REG | L | 5-2 | +112 | U | 9.5 |
| Sep 7, 2021 | vs Minnesota | REG | L | 3-0 | -125 | U | 10.5 |
| Sep 8, 2021 | vs Minnesota | REG | L | 3-0 | -125 | U | 9 |
| Sep 9, 2021 | vs Minnesota | REG | W | 4-1 | -158 | U | 9 |
| Sep 10, 2021 | vs Milwaukee | REG | L | 10-3 | +123 | O | 9 |
| Sep 11, 2021 | vs Milwaukee | REG | L | 3-0 | +170 | U | 9 |
| Sep 12, 2021 | vs Milwaukee | REG | L | 11-1 | -105 | O | 9.5 |
| Sep 14, 2021 | @ Minnesota | REG | W | 3-1 | +110 | U | 6 |
| Sep 14, 2021 | @ Minnesota | REG | L | 6-3 | +110 | O | 7.5 |
| Sep 15, 2021 | @ Minnesota | REG | W | 12-3 | +102 | O | 9 |
| Sep 17, 2021 | @ NY Yankees | REG | L | 8-0 | +170 | U | 9 |
| Sep 18, 2021 | @ NY Yankees | REG | W | 11-3 | +175 | O | 9.5 |
| Sep 19, 2021 | @ NY Yankees | REG | W | 11-1 | +285 | O | 8.5 |
| Sep 20, 2021 | vs Kansas City | REG | L | 7-2 | -156 | O | 7 |
| Sep 20, 2021 | vs Kansas City | REG | L | 4-2 | -127 | U | 7.5 |
| Sep 21, 2021 | vs Kansas City | REG | W | 4-1 | -155 | U | 9 |
| Sep 23, 2021 | vs Chi White Sox | REG | L | 7-2 | +125 | O | 7 |
| Sep 23, 2021 | vs Chi White Sox | REG | W | 5-3 | +107 | O | 6 |
| Sep 24, 2021 | vs Chi White Sox | REG | L | 1-0 | +100 | U | 8 |
| Sep 25, 2021 | vs Chi White Sox | REG | W | 6-0 | +160 | U | 8.5 |
| Sep 26, 2021 | vs Chi White Sox | REG | L | 5-2 | +130 | U | 8.5 |
| Sep 27, 2021 | vs Kansas City | REG | W | 8-3 | -175 | O | 9.5 |
| Sep 28, 2021 | @ Kansas City | REG | L | 6-4 | +110 | O | 9 |
| Sep 29, 2021 | @ Kansas City | REG | L | 10-5 | -115 | O | 9 |
| Sep 30, 2021 | @ Kansas City | REG | W | 6-1 | -151 | U | 8.5 |
| Oct 1, 2021 | @ Texas | REG | W | 9-6 | -120 | O | 8.5 |
| Oct 2, 2021 | @ Texas | REG | L | 7-2 | -140 | O | 8.5 |
| Oct 3, 2021 | @ Texas | REG | W | 6-0 | +100 | U | 8 |
