Northwestern Wildcats - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 3, 2021 | vs Michigan State | REG | L | 38-21 | L | -3 | O | 45.5 |
| Sep 11, 2021 | vs Indiana State | REG | W | 24-6 | L | -28.5 | U | 46 |
| Sep 18, 2021 | @ Duke | REG | L | 30-23 | L | -2.5 | O | 50 |
| Sep 25, 2021 | vs Ohio | REG | W | 35-6 | W | -14 | U | 47.5 |
| Oct 2, 2021 | @ Nebraska | REG | L | 56-7 | L | +11 | O | 51.5 |
| Oct 16, 2021 | vs Rutgers | REG | W | 21-7 | W | +2.5 | U | 45 |
| Oct 23, 2021 | @ Michigan | REG | L | 33-7 | L | +23.5 | U | 51 |
| Oct 30, 2021 | vs Minnesota | REG | L | 41-14 | L | +7.5 | O | 43.5 |
| Nov 6, 2021 | vs Iowa | REG | L | 17-12 | W | +12 | U | 40.5 |
| Nov 13, 2021 | @ Wisconsin | REG | L | 35-7 | L | +25.5 | O | 41.5 |
| Nov 20, 2021 | vs Purdue | REG | L | 32-14 | L | +11 | U | 47.5 |
| Nov 27, 2021 | @ Illinois | REG | L | 47-14 | L | +7 | O | 44.5 |
