UTSA Roadrunners - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 4, 2021 | @ Illinois | REG | W | 37-30 | W | +4.5 | O | 52 |
| Sep 11, 2021 | vs Lamar | REG | W | 54-0 | W | -40 | U | 65 |
| Sep 18, 2021 | vs Middle Tennessee | REG | W | 27-13 | W | -11.5 | U | 59.5 |
| Sep 25, 2021 | @ Memphis | REG | W | 31-28 | W | +3 | U | 66.5 |
| Oct 2, 2021 | vs Nevada-Las Vegas | REG | W | 24-17 | L | -21.5 | U | 55.5 |
| Oct 9, 2021 | @ Western Kentucky | REG | W | 52-46 | W | +3 | O | 71 |
| Oct 16, 2021 | vs Rice | REG | W | 45-0 | W | -17 | U | 53 |
| Oct 23, 2021 | @ Louisiana Tech | REG | W | 45-16 | W | -5.5 | O | 59.5 |
| Nov 6, 2021 | @ Texas El Paso | REG | W | 44-23 | W | -12 | O | 53 |
| Nov 13, 2021 | vs Southern Miss | REG | W | 27-17 | L | -32.5 | U | 54.5 |
| Nov 20, 2021 | vs Alabama-Birmingham | REG | W | 34-31 | L | -3.5 | O | 53.5 |
| Nov 27, 2021 | @ North Texas | REG | L | 45-23 | L | -8.5 | O | 59.5 |
| Dec 3, 2021 | vs Western Kentucky | REG | W | 49-41 | W | +3.5 | O | 74.5 |
| Dec 21, 2021 | @ San Diego State | PST | L | 38-24 | L | +3 | O | 48.5 |
