| loss | Clay Guida | 15 19 | 0 1 | 0 1 | +250 -333 | FN Dec 2, 2023 | DEC | 3 | 1:27 |
| loss | Clay Guida | 19 44 | 0 0 | 0 0 | +230 -280 | FN Apr 15, 2023 | DEC | 3 | 1:27 |
| win | Clay Guida | 95 77 | 4 0 | 0 0 | +170 -200 | FN Dec 3, 2022 | DEC | 3 | 1:27 |
| loss | Clay Guida | 4 11 | 0 0 | 0 2 | -110 -110 | FN Apr 23, 2022 | Submission | 1 | 1:46 |
| win | Clay Guida | 50 65 | 2 0 | 1 0 | +186 -214 | FN Dec 4, 2021 | Submission | 2 | 3:07 |
| loss | Clay Guida | 72 101 | 0 0 | 0 0 | +150 -185 | FN Aug 21, 2021 | DEC | 3 | 1:27 |
| win | Clay Guida | 65 70 | 3 0 | 1 0 | +170 -210 | FN Feb 6, 2021 | DEC | 3 | 1:27 |
| loss | Clay Guida | 27 90 | 3 2 | 0 2 | +205 -290 | FN Jun 20, 2020 | DEC | 3 | 1:27 |
| loss | Clay Guida | | | | +125 -155 | FN Aug 3, 2019 | Submission | 1 | :58 |
| win | Clay Guida BJ Penn | 113 74 | 1 0 | 0 0 | -700 +450 | UFC 237 May 11, 2019 | DEC | 3 | 5:00 |
| loss | Clay Guida | 9 14 | 0 0 | 0 1 | +128 -148 | UFC 225 Jun 9, 2018 | Submission | 1 | 2:18 |
| win | Clay Guida | 31 1 | 0 0 | 0 0 | -125 +105 | FN Nov 11, 2017 | KO/TKO | 1 | 1:07 |
| win | Clay Guida Erik Koch | 133 17 | 2 0 | 0 0 | +290 -350 | FN Jun 25, 2017 | DEC | 3 | 5:00 |
| loss | Clay Guida | 70 62 | 0 0 | 0 0 | +200 -240 | UFC 199 Jun 4, 2016 | KO/TKO | 3 | 4:40 |
| loss | Clay Guida Thiago Tavares | 3 2 | 1 0 | 0 1 | -162 +142 | FN Nov 7, 2015 | Submission | 1 | :39 |
| win | Clay Guida Robert Peralta | 44 41 | 6 0 | 1 0 | -250 +210 | FN Apr 4, 2015 | DEC | 3 | 5:00 |
| loss | Clay Guida Dennis Bermudez | 39 66 | 0 2 | 0 1 | +141 -161 | UFC on Fox Jul 26, 2014 | Submission | 2 | 2:57 |
| win | Clay Guida Tatsuya Kawajiri | 92 36 | 3 1 | 0 1 | -136 +116 | FN Apr 11, 2014 | DEC | 3 | 5:00 |
| loss | Clay Guida Chad Mendes | 19 40 | 0 3 | 0 1 | +375 -500 | UFC 164 Aug 31, 2013 | KO/TKO | 3 | :30 |
| win | Clay Guida Hatsu Hioki | 40 74 | 3 0 | 0 1 | -240 +200 | UFC on Fox Jan 26, 2013 | DEC | 3 | 5:00 |
| loss | Clay Guida Gray Maynard | 49 52 | 0 1 | 0 1 | +270 -325 | UFC on FX Jun 22, 2012 | DEC | 5 | 5:00 |
| loss | Clay Guida Benson Henderson | 35 102 | 2 2 | 4 0 | | UFC on Fox Nov 12, 2011 | DEC | 3 | 5:00 |
| win | Clay Guida Anthony Pettis | 63 42 | 5 0 | 0 1 | | TUF Jun 4, 2011 | DEC | 3 | 5:00 |
| win | Clay Guida Takanori Gomi | 16 14 | 3 0 | 2 0 | | UFC 125 Jan 2, 2011 | Submission | 2 | 4:27 |
| win | Clay Guida | 47 29 | 2 1 | 0 0 | | UFC 117 Aug 7, 2010 | Submission | 3 | 1:51 |
| win | Clay Guida Shannon Gugerty | 72 6 | 2 0 | 1 3 | | UFC on Versus Mar 21, 2010 | Submission | 2 | 3:40 |
| loss | Clay Guida Kenny Florian | 14 43 | 0 1 | 0 1 | | UFC 107 Dec 12, 2009 | Submission | 2 | 2:19 |
| loss | Clay Guida Diego Sanchez | 57 80 | 2 1 | 0 3 | | TUF Jun 20, 2009 | DEC | 3 | 5:00 |
| win | Clay Guida | 75 70 | 4 0 | 1 0 | | UFC 94 Jan 31, 2009 | DEC | 3 | 5:00 |
| win | Clay Guida Mac Danzig | 67 64 | 10 1 | 0 0 | | FN Sep 17, 2008 | DEC | 3 | 5:00 |
| win | Clay Guida Samy Schiavo | 24 4 | 1 0 | 0 0 | | FN Apr 2, 2008 | KO/TKO | 1 | 4:15 |
| loss | Clay Guida Roger Huerta | 100 53 | 6 0 | 1 3 | | TUF Dec 8, 2007 | Submission | 3 | :51 |
| win | Clay Guida Marcus Aurelio | 71 47 | 0 0 | 0 0 | | UFC 74 Aug 25, 2007 | DEC | 3 | 5:00 |
| loss | Clay Guida Tyson Griffin | 82 87 | 4 2 | 2 2 | | UFC 72 Jun 16, 2007 | DEC | 3 | 5:00 |
| loss | Clay Guida Din Thomas | 93 51 | 5 0 | 0 1 | | FN Jan 25, 2007 | DEC | 3 | 5:00 |
| win | Clay Guida Justin James | 93 28 | 2 0 | 2 1 | | UFC 64 Oct 14, 2006 | Submission | 2 | 4:42 |
