| win | Joe Lauzon | | | | -106 -116 | FN Oct 18, 2019 | KO/TKO | 1 | 1:35 |
| loss | Joe Lauzon | 49 135 | 0 0 | 0 0 | -145 +125 | UFC 223 Apr 7, 2018 | KO/TKO | 2 | 5:00 |
| loss | Joe Lauzon | 1 31 | 0 0 | 0 0 | +105 -125 | FN Nov 11, 2017 | KO/TKO | 1 | 1:07 |
| loss | Joe Lauzon Stevie Ray | 65 139 | 5 0 | 1 1 | +135 -165 | FN Apr 22, 2017 | DEC | 3 | 5:00 |
| win | Joe Lauzon Marcin Held | 44 32 | 1 5 | 1 0 | -130 +110 | FN Jan 15, 2017 | DEC | 3 | 5:00 |
| loss | Joe Lauzon | 92 97 | 3 0 | 1 0 | -140 +120 | FN Aug 27, 2016 | DEC | 3 | 5:00 |
| win | Joe Lauzon Diego Sanchez | 28 7 | 0 0 | 0 0 | +105 -125 | UFC 200 Jul 9, 2016 | KO/TKO | 1 | 1:26 |
| loss | Joe Lauzon Evan Dunham | 44 147 | 0 1 | 0 0 | +155 -180 | TUF 22 Dec 12, 2015 | DEC | 3 | 5:00 |
| win | Joe Lauzon Takanori Gomi | 25 7 | 1 0 | 0 0 | -300 +250 | UFC on Fox Jul 25, 2015 | KO/TKO | 1 | 2:37 |
| loss | Joe Lauzon Al Iaquinta | 32 63 | 0 1 | 0 0 | +167 -192 | UFC 183 Jan 31, 2015 | KO/TKO | 2 | 3:34 |
| win | Joe Lauzon | 42 42 | 2 1 | 0 0 | +185 -220 | FN Sep 5, 2014 | TKO - Doctor's Stoppage | 2 | 2:14 |
| win | Joe Lauzon Mac Danzig | 80 91 | 3 0 | 2 0 | -175 +145 | UFC on Fox Dec 14, 2013 | DEC | 3 | 5:00 |
| loss | Joe Lauzon | 28 119 | 0 2 | 0 0 | -240 +190 | FN Aug 17, 2013 | DEC | 3 | 5:00 |
| loss | Joe Lauzon | 40 96 | 0 1 | 3 2 | +165 -190 | UFC 155 Dec 29, 2012 | DEC | 3 | 5:00 |
| win | Joe Lauzon Jamie Varner | 55 84 | 2 2 | 1 1 | -120 +100 | UFC on FOX Aug 4, 2012 | Submission | 3 | 2:44 |
| loss | Joe Lauzon Anthony Pettis | 0 9 | 0 0 | 0 0 | +240 -285 | UFC 144 Feb 26, 2012 | KO/TKO | 1 | 1:21 |
| win | Joe Lauzon Melvin Guillard | 2 3 | 0 0 | 1 0 | | UFC 136 Oct 8, 2011 | Submission | 1 | :47 |
| win | Joe Lauzon Curt Warburton | 12 5 | 0 0 | 1 0 | | UFC Live on Versus Jun 26, 2011 | Submission | 1 | 1:58 |
| loss | Joe Lauzon George Sotiropoulos | 24 24 | 0 3 | 0 2 | | UFC 123 Nov 21, 2010 | Submission | 2 | 2:43 |
| win | Joe Lauzon Gabe Ruediger | 19 1 | 2 0 | 1 0 | | UFC 118 Aug 28, 2010 | Submission | 1 | 2:01 |
| loss | Joe Lauzon Sam Stout | 33 110 | 4 0 | 2 0 | | UFC 108 Jan 2, 2010 | DEC | 3 | 5:00 |
| win | Joe Lauzon Jeremy Stephens | 32 25 | 2 1 | 4 0 | | FN Feb 7, 2009 | Submission | 2 | 4:43 |
| win | Joe Lauzon Kyle Bradley | 30 19 | 1 0 | 2 0 | | FN Sep 17, 2008 | KO/TKO | 2 | 1:34 |
| loss | Joe Lauzon Kenny Florian | 9 115 | 2 2 | 2 0 | | FN Apr 2, 2008 | KO/TKO | 2 | 3:28 |
| win | Joe Lauzon Jason Reinhardt | 8 1 | 1 0 | 1 0 | | UFC 78 Nov 17, 2007 | Submission | 1 | 1:14 |
| win | Joe Lauzon Brandon Melendez | 27 12 | 3 0 | 6 0 | | TUF 5 Jun 23, 2007 | Submission | 2 | 2:09 |
| win | Joe Lauzon Jens Pulver | 9 0 | 1 0 | 0 0 | | UFC 63 Sep 23, 2006 | KO/TKO | 1 | :48 |
