| win | Matt Brown | 22 17 | 0 1 | 0 0 | +190 -225 | FN May 13, 2023 | KO/TKO | 1 | 5:08 |
| loss | Matt Brown | 95 186 | 5 0 | 0 0 | -115 -115 | FN Mar 26, 2022 | DEC | 3 | 1:27 |
| win | Matt Brown Dhiego Lima | 30 23 | 0 0 | 0 0 | +160 -200 | FN Jun 19, 2021 | KO/TKO | 2 | 3:36 |
| loss | Matt Brown Carlos Condit | 28 39 | 1 2 | 0 0 | +170 -200 | FN Jan 16, 2021 | DEC | 3 | 1:27 |
| loss | Matt Brown | 33 42 | 0 0 | 0 0 | +120 -150 | FN May 16, 2020 | KO/TKO | 2 | :18 |
| win | Matt Brown Ben Saunders | | | | -350 +270 | UFC 245 Dec 14, 2019 | KO/TKO | 2 | 4:55 |
| win | Matt Brown Diego Sanchez | 20 13 | 0 0 | 0 0 | -360 +280 | FN Nov 11, 2017 | KO/TKO | 1 | 3:44 |
| loss | Matt Brown | 73 64 | 0 0 | 1 0 | +240 -280 | UFC 206 Dec 10, 2016 | KO/TKO | 3 | :34 |
| loss | Matt Brown Jake Ellenberger | 7 29 | 0 0 | 0 0 | -300 +250 | UFC 201 Jul 30, 2016 | KO/TKO | 1 | 1:46 |
| loss | Matt Brown Demian Maia | 29 91 | 0 3 | 0 2 | +250 -350 | UFC 198 May 14, 2016 | Submission | 3 | 4:31 |
| win | Matt Brown | 26 24 | 1 0 | 1 0 | -148 +128 | UFC 189 Jul 11, 2015 | Submission | 1 | 4:44 |
| loss | Matt Brown Johny Hendricks | 39 85 | 0 9 | 0 0 | +285 -350 | UFC 185 Mar 14, 2015 | DEC | 3 | 5:00 |
| loss | Matt Brown | 89 87 | 2 2 | 0 0 | +265 -315 | UFC on Fox Jul 26, 2014 | DEC | 5 | 5:00 |
| win | Matt Brown Erick Silva | 161 39 | 5 0 | 4 1 | +220 -260 | FN May 10, 2014 | KO/TKO | 3 | 2:11 |
| win | Matt Brown Mike Pyle | 10 0 | 0 0 | 0 0 | -135 +105 | FN Aug 17, 2013 | KO/TKO | 1 | :29 |
| win | Matt Brown Jordan Mein | 41 25 | 0 0 | 1 0 | +275 -330 | UFC on FOX Apr 20, 2013 | KO/TKO | 2 | 1:00 |
| win | Matt Brown Mike Swick | 37 19 | 1 0 | 2 0 | +115 -155 | UFC on Fox Dec 8, 2012 | KO/TKO | 2 | 2:31 |
| win | Matt Brown Luis Ramos | 74 26 | 0 1 | 0 0 | | UFC on FX Jun 22, 2012 | KO/TKO | 2 | 4:20 |
| win | Matt Brown | 91 78 | 5 0 | 1 0 | +190 -220 | UFC 145 Apr 21, 2012 | DEC | 3 | 5:00 |
| win | Matt Brown Chris Cope | 48 24 | 1 0 | 0 0 | -350 +290 | UFC 143 Feb 5, 2012 | KO/TKO | 2 | 1:19 |
| loss | Matt Brown Seth Baczynski | 28 22 | 1 1 | 0 1 | | UFC 139 Nov 19, 2011 | Submission | 2 | :42 |
| win | Matt Brown John Howard | 96 29 | 3 5 | 3 0 | | UFC Live on Versus Jun 26, 2011 | DEC | 3 | 5:00 |
| loss | Matt Brown Brian Foster | 23 36 | 1 3 | 1 2 | | UFC 123 Nov 21, 2010 | Submission | 2 | 2:11 |
| loss | Matt Brown Chris Lytle | 29 40 | 1 0 | 1 4 | | UFC 116 Jul 3, 2010 | Submission | 2 | 2:02 |
| loss | Matt Brown Ricardo Almeida | 23 24 | 0 5 | 0 1 | | UFC 111 Mar 27, 2010 | Submission | 2 | 3:30 |
| win | Matt Brown James Wilks | 67 58 | 0 1 | 3 3 | | UFC 105 Nov 14, 2009 | KO/TKO | 3 | 2:27 |
| win | Matt Brown Pete Sell | 44 0 | 0 0 | 0 0 | | UFC 96 Mar 7, 2009 | KO/TKO | 1 | 1:32 |
| win | Matt Brown Ryan Thomas | 20 76 | 1 5 | 3 0 | | UFC 91 Nov 15, 2008 | Submission | 2 | :57 |
| loss | Matt Brown Dong Hyun Kim | 91 18 | 1 3 | 2 1 | | UFC 88 Sep 6, 2008 | DEC | 3 | 5:00 |
| win | Matt Brown Matt Arroyo | 53 34 | 0 2 | 1 0 | | TUF Jun 21, 2008 | KO/TKO | 2 | 3:40 |
