We’re only two weeks into the 2016 NFL season, but the Buffalo Bills (0-2) already have their collective fingers over the panic button. The winless Bills will look to get things back on track at home against the Arizona Cardinals (1-1) on Sunday.
- The Cardinals are 2-6 ATS in their last eight games as a favorite of 4.0 or more.
- The Bills are 2-14 SU in their last 16 games with a closing total of 47.0 or more.
- The total has gone UNDER in 10 of the Bills' last 13 games as underdog.
The good news for Bills fans and backers alike is they’ve had Arizona’s number lately. Buffalo is 5-1 SU and ATS in their last six get-togethers with the Cards. OVER bettors have also been profiting in this matchup, as four of the last five games between the teams have gone above the closing total.
Sportsbooks opened the Bills as 4-point underdogs, with the OVER/UNDER at 47.
As a result of Arizona’s dynamic offense, oddsmakers tend to tab them with high totals. But totals bettors shouldn’t automatically assume that’s led to cashed OVER bets. Including last season, the UNDER is 7-3 in the Cardinals’ last 10 games.
The Cardinals couldn’t get the job done in the season opener versus New England, but they bounced back in a big way in Week 2 by pummeling Tampa Bay 40-7. The ageless Carson Palmer continues to sling it under center, compiling five touchdowns and 579 passing yards.
Buffalo mustered a measly seven points in Week 1’s loss to Baltimore, and their defense showed some major holes in a 37-31 setback to the division rival New York Jets last weekend. For a franchise that hasn’t made the playoffs since 1999, it’s safe to say the sky could start to fall in Buffalo if they drop this game.
Sportsbook Odds & Computer Pick
The Arizona Cardinals betting odds line opened as -5.5-point favorites in this one at most sportsbooks tracked here at Odds Shark (including Sportsbook), while the total was hovering around 47 at most shops.
A 22-19 result in favor of the Cardinals is the prediction by the Odds Shark handicapping pick engine. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.
Arizona Cardinals vs Buffalo Bills Matchup
Team Betting Records & Power Rankings
Supporters of the Arizona Cardinals have seen them go 1-1 and 1-1 ATS so far this season, while the Buffalo Bills are at 0-2 and 0-2 ATS. In totals betting, the Bills are 1-1, while the Cardinals are 0-1-1. Stay Informed: follow us on Twitter for odds specials, betting line moves and Buffalo vs Arizona injuries news.
The game pits the Buffalo Bills, currently No. 16 in our Odds Shark NFL Power Rankings, against the Arizona Cardinals, who rate No. 4 in the latest survey.
Recent Outings Betting Recap
Carson Palmer dusted the Buccaneers secondary for 3 TDs last time out as the Cardinals defeated Tampa Bay 40-7 at University of Phoenix Stadium.
Tyrod Taylor beat the Jets secondary for 3 TDs last time out, but the Bills lost to New York 37-31 at Ralph Wilson Stadium.
- Arizona is 1-4 ATS in its last 5 games
- Arizona is 11-3 SU in its last 14 games
- The total has gone UNDER in 7 of Arizona's last 10 games
- Arizona is 4-2 ATS in its last 6 games on the road
- Buffalo is 2-4 ATS in its last 6 games
- Buffalo is 2-4 SU in its last 6 games
- The total has gone UNDER in 4 of Buffalo's last 6 games
- Buffalo is 4-1 ATS in its last 5 games at home
Next Betting Matchups
Arizona home to Los Angeles, Sunday, October 2nd
Buffalo at New England, Sunday, October 2nd
