MNF Odds: Eagles vs Colts Week 2 Pick

The OVER has gone 4-0 in the Philadelphia Eagles' last four games as road underdogs as they try to follow up their Week 1 comeback victory with a win over the Colts in Indianapolis on Monday Night Football.

Indy has followed up a loss with an ATS win 13 straight times. They are in this situation after losing in Denver with the line settling in at -3 over at Sportsbook today.

Our database has the number at 13-2 ATS when a season-ending loss is considered in the data. But in the same season, they have never failed to cover coming off a loss in 13 tries.

The Eagles rallied for a 34-17 win over the Jaguars in their opener, and the OVER has also gone 6-1 in their last seven games against teams from the AFC South. The Colts, who lost to the Broncos in primetime in their season opener, are 3-1 both SU and ATS in their last four home games against teams from the NFC.

Philadelphia Eagles vs Indianapolis Colts Sportsbook Odds and Betting Line

The Philadelphia Eagles betting odds line opened as 2.5-point underdogs in this one at most sportsbooks tracked here at Odds Shark (including Sportsbook), while the total was hovering around 52.5 at most shops, including bonus specialists Sportsbook.

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Computer Prediction: Philadelphia Eagles vs Indianapolis Colts Pick

A 26.4-25 result in favor of the Eagles is the prediction by the Odds Shark handicapping pick engine. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.

Philadelphia Eagles vs Indianapolis Colts Odds and Stats.

Team Betting Records & Power Rankings

The Indianapolis Colts sport a record of 0-1 and 1-0 ATS heading into this betting matchup, while the Philadelphia Eagles sit at 1-0 and 1-0 ATS on the season. The over under totals records are 1-0 for the Colts and 1-0 for the Eagles. Stay Informed: follow us on Twitter for odds specials, betting line moves and Indianapolis vs Philadelphia injuries news.

The game pits the Indianapolis Colts, currently No. 16 in our Odds Shark NFL Power Rankings, against the Philadelphia Eagles, who rate No. 6 in the latest survey.

Recent Outings Betting Recap

Last time out for Philadelphia, they were a 34-17 Sportsbook as they battled the Jaguars at home. The Eagles covered in the match as a -10-point favorite, while 51 combined points moved the game OVER for totals bettors. Nick Foles led his team to victory last time out, throwing for 322 yards Sunday as the Eagles downed the Jaguars 34-17 at Lincoln Financial Field.

The Colts were a 31-24 loser in their most recent outing on the road against the Broncos. They covered the +8.5-point spread as underdogs, while the total score (55) made Sportsbooks of OVER bettors. In their last game, Indianapolis's aerial attack generated 370 yards but it was the Broncos coming away with a 31-24 victory over Indianapolis at Sports Authority Field at Mile High.

Philadelphia Eagles vs Indianapolis Colts Betting Odds Trends

Philadelphia is 8-2 SU in its last 10 games
The total has gone OVER in 4 of Philadelphia's last 6 games
Philadelphia is 4-2 ATS in its last 6 games on the road
Philadelphia is 5-1 SU in its last 6 games on the road
Indianapolis is 5-1 ATS in its last 6 games
Indianapolis is 4-2 SU in its last 6 games
The total has gone OVER in 9 of Indianapolis's last 13 games
Indianapolis is 6-1 ATS in its last 7 games at home