The Seahawks sit as slight favorites for a massive NFC West battle against the Cardinals this weekend.
With all four NFC West squads separated by a single win, this game will help define the division race down the stretch. Despite leading the division at 6-4, the Cardinals are 1.5-point road underdogs at Seattle, with the Seahawks sitting at -112 on the moneyline.
The Cardinals still remain the division favorites at -120 and are the sportsbooks' biggest liability to win this year, per BetMGM data. So, why don't we bank on an upset this week to keep this Cardinals miracle run going?
I'll break down complete Cardinals vs Seahawks Week 12 odds and picks below:
Cardinals vs Seahawks Odds Week 12
Arizona Cardinals vs Seattle Seahawks, Nov. 24, 4:25 pm ET
| Team | Point Spread | Moneyline | Totals |
|---|---|---|---|
| Cardinals | +1.5 (-120) | -104 | O 47.5 (-110) |
| Seahawks | -1.5 (-102) | -112 | U 47.5 (-110) |
As of November 19th at Caesars Sportsbook
Cardinals vs Seahawks Picks Week 12
Cardinals Moneyline (-104)
I'm taking the slight underdogs in this one, predicting the Cardinals to stay hot with a win over the Seahawks.
The Cardinals have won their last four games, defeating the Jets, Bears, Dolphins, and Cardinals by a combined 48 points. Arizona's only losses this season have come against the Bills, Lions, Commanders, and Packers — four teams with real aspirations to win playoff games.
The Seahawks, on the other hand, have been up-and-down. They're 2-4 in their last six, including a loss to the lowly Giants. Seattle ranks far behind Arizona in expected record, point differential, and Net Expected Points Added. In my eyes, the Cardinals should be slight favorites in this divisional matchup, so it's an easy underdog bet on the Cards for me.
The Cardinals also enter this game coming off a bye week, giving them the rest advantage for this Week 12 contest.
Cardinals vs Seahawks Prop Pick
Geno Smith To Throw An Interception (-130)
Geno Smith basically is the Seahawks offense. They've let him throw the ball at least 28 times every game since Week 1. He leads the entire league with 37.4 passing attempts per game. But, with the ball in the air that much, interceptions have been inevitable for Smith. The Seahawks QB has 11 interceptions on the year, throwing at least one in seven of 10 games.
In four games against the Cardinals since becoming the Seahawks QB in 2022, Geno has thrown two picks.
Cardinals vs Seahawks Betting Trends
- The Cardinals are 4-8 in their last 12 road games
- The Seahawks are 1-6 against the spread in their last seven home games
- The OVER has hit in the Seahawks' last nine games as favorites
- Marvin Harrison Jr. has gone UNDER 54.5 rec yards in six of his last seven games (He's -120 to go U54.5 yards this week, at FanDuel)
These betting trends are courtesy of Outlier's NFL Insights:
