The Buffalo Bills opened up as a 4-point favorite on the road over the Indianapolis Colts in a Week 10 contest and the Over/Under total on this game was set at 47.5 at FanDuel. A few pennies have come in on Bills and the line has ticked up to -4.5, even -5 in some spots. The O/U has not moved down a point to 46.5.
The last time these teams met was in the middle of the 2021 season. The game was in Buffalo but the Bills (-7) got blown away by the Colts, 41-15. The O/U total was 49.5 and went high. Josh Allen was slinging for the Bills and had a kinda crappy game (21 of 35 for 209 yards with 2 TDs and 2 INTs).
And if look-aheads are part of your handicapping homework, the Bills will host the defending Super Bowl Champions Chiefs, while the Colts head to New York for a matchup against the Jets.
Buffalo Bills vs Indianapolis Colts Odds Week 10
Buffalo Bills vs Indianapolis Colts, Nov. 10, 1:00 pm ET
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Buffalo Bills | -4.5 (-104) | -200 | O46.5 (-105) |
| Indianapolis Colts | +4.5 (-118) | +168 | U46.5 (-115) |
Odds as of Nov. 5 at FanDuel
Buffalo Bills vs Indianapolis Colts Pick Week 10
Bills -4.5 (-104) at FanDuel
For almost 17 years, the Patriots ruled the AFC East, but then Tom Brady left and Josh Allen decided to take the crown. Buffalo is sitting at 7-2 and with the Jets (3-6), Dolphins (2-6) and Patriots (2-7) all PATHETIC, so basically, the East is a lock for the Bills. And the AFC as a whole could turn into a Buffalo party as well. The Bills have the best point differential in the conference at +87. The only team that has a better point differential in the NFL is the Lions at +110.
And most of the damage is being done with the right arm of QB Josh Allen, because the running game is kinda just average. Allen has been a top tier QB for a few years now, but it looks like 2024 might be his best season yet. He has completed 168 of 262 (64.1%) for 2,001 yards with 17 TDs and only 2 INTs. The reason that we're suggesting this could be his best season yet is the way he has cut down dramatically on INTs.
Since coming into the league from Wyoming in 2018, Allen has thrown 12, nine, 10, 15, 14 and 18 INTs. This season at the halfway point he has TWO. Not saying Josh is gonna throw just four INTs all year, but MAN, he is WAY sharper this season.
Now we have to look at the the other arm, 39 year old Grandpa Joe Flacco. Not disrespecting Flacco, and he is not a Grandpa yet, but 39 in the NFL is dinosaur territory. Think about it. Josh Allen was in middle school when Old Joe started his career in Baltimore.
Flacco is capable and can still get the job done. He was okay last week in a loss to the Vikings, hitting on 16 of 27 (59.3%) for 179 yards with NO TDs and 1 INT. But the real issue here is mobility. Watching Flacco move is kinda like watching Giancarlo Stanton rounding third base and taking a WEEK to get to home plate. The Buffalo defense is pretty stout and not having to worry about a QB dancing or escaping the pocket will lead to another primo effort.
Buffalo and Indy both beat Miami and both lost to Houston. But a common opponent that you should focus on is Jacksonville. The Bills SMOKED the Jaguars 47-10 while the Colts came up on the short end of a 37-34 score against the Jags. Flacco was sacked four times in that game and three times against Minny last week. If the line holds steady at -4.5, you could buy the hook down to -4, or, even try the money line. Either way, we're gonna CIRCLE the wagons!
Buffalo Bills vs Indianapolis Colts Betting Trends
- Colts have covered six of their last seven.
- Colts are on an 0-4 run to the UNDER.
- Bills have won 13 of the last 16 games overall.
