Jaguars vs Bills Odds & Picks Week 3: Jags Are In Trouble

We've got some Monday Night Football Jaguars vs Bills odds for Week 3, with the Bills slated as sizeable favorites.

Buffalo opened as a 3.5-point favorite, though the line has now moved to -5. The Bills are 2-0 on the season, facing off against a Jaguars team that's looked pretty bad heading into MNF.

Check out my full Jaguars vs Bills odds analysis & picks below:

Jaguars vs Bills Odds Week 3

Jacksonville Jaguars vs Buffalo Bills, Sept. 23, 7:30 pm ET

As of September 18 at FanDuel

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Jaguars vs Bills Picks Week 3

Bills -5 (-110)

Folks, the Jacksonville Jaguars might just be bad. The Jags are 0-2, losing to a flawed Dolphins team and even more flawed Browns side. They rank bottom-10 in net EPA. Perhaps most concerning, Trevor Lawrence is rocking a 50% completion rate with just one passing TD through two games. Nothing's going right in Jacksonville.

With Lawrence at QB and some big names across the roster, expectations have been high for this Jacksonville side. But, those expectations have only hurt the Jags when it comes to betting the last year or so, as they're 2-6 against the spread in their last eight.

The Jags have been torched by opposing QBs so far this year, allowing the third-most passing yards against and a rushing touchdown to an opposing QB, too. With Josh Allen lining up across from them this week, that problem isn't getting any better. Allen has 20 passing touchdowns in eight career Monday Night Football games.

Dating back to last year, the Bills have won four-straight regular season games by over five points. This line doesn't scare me at all.

Picks as of September 18th at 2:20 pm ET

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